Rhode Island Multistate Pharmacy Jurisprudence (MPJE) Practice Exam

Immediate use sterile compounds not mixed in an ISO 5 environment must be used within what time frame?

1. 30 minutes

2. 1 hour

3. 2 hours

4. 24 hours

The correct answer is: 1 hour

Immediate use sterile compounds that are not prepared in an ISO 5 environment must be used within 1 hour to ensure their safety and efficacy. This time frame is critical because sterile compounds, when not prepared in a controlled environment, are at an increased risk for microbial contamination. By using the compound promptly within 1 hour, the risk of contamination is minimized, and the integrity of the sterile preparation is better maintained. In practice, hospitals and pharmacies must adhere to this guideline to ensure patient safety. Immediate-use sterile compounding often occurs in emergency situations where patients require rapid medication administration, and therefore, the regulations emphasize the need for quick use to prevent contamination. The other options present varying time frames that do not align with this standard. Longer time frames would increase the risk of degradation and contamination, which is why they are not considered acceptable for immediate use sterile preparations outside of an ISO 5 environment.